Daily Journal Digest — 2026-07-25¶
過去 24 小時新增：Transplant ID × 15、One Health × 12、Food Security × 10，共 37 篇。
⭐ 今日亮點¶
- When silos cannot be broken: Rethinking integration and coexistence in one health
One Health治理框架很值得重想 - The Assessment of Air Quality in Unprotected Hospital Areas: An Opinion Paper
免疫低下病房外空氣風險被低估 - One Health implementation for rabies elimination in India by 2030: Progress, governance, challenges, and policy alignment
rabies消除凸顯One Health落地缺口
🔬 深入評讀¶
When silos cannot be broken: Rethinking integration and coexistence in one health¶
One Health | IF 5.7 | DOI | PMID 42494547
- 設計：這是 One Health 實作概念的評論文章，從制度、學科、資料、地理與文化 silos 重新檢視「打破 silos」這個常見口號。文章不是系統性回顧，而是提出治理與協作框架。
- 樣本：不適用傳統樣本數；文章涵蓋 human、animal、environmental health 之間跨部門協作的制度情境。重點放在 technical、relational 與 governance bridges 如何讓不同系統協作而不抹平專業分工。
- 關鍵論點：核心論點是 silos 不只是不良障礙，也保存專業、問責與制度連貫性；One Health 的任務不一定是消滅 silos，而是設計可持續的橋接機制。這對 zoonoses、AMR 與環境健康治理特別重要，因為問題本身需要跨域，但執行責任仍常落在各自制度內。
- Limitation：本文屬評論／概念框架，沒有系統性檢索、預先定義的納入標準或可量化 outcome。其可轉化性取決於各國治理結構，不能直接推論哪一種 bridge 一定改善 surveillance、疫苗覆蓋或 AMR 控制。
- Bottom line：One Health 實務上不必迷信「打破 silos」，更該問如何在保留專業問責下建立能運作的跨域橋接。
The Assessment of Air Quality in Unprotected Hospital Areas: An Opinion Paper¶
J Hosp Infect | DOI | PMID 42492844
- 設計：這是 J Hosp Infect 的 opinion paper，包含 2015–2025 年 indoor air quality in unprotected hospital areas（IAQ-U）的敘述性回顧，並檢視部分醫療場域 IAQ 建議。文章同時提出 ESCMID 可協調歐洲多中心 pilot study 的政策建議。
- 樣本：不適用原始研究樣本數；涵蓋醫院 protected 與 unprotected areas 的空氣品質證據與建議。關鍵族群是暴露於非 protected 區域的 immunocompromised patients，尤其是可能受 airborne healthcare-associated infections 影響者。
- 關鍵論點：作者指出 protected zones 已有較明確空氣品質建議，但 unprotected hospital areas 缺乏一致評估與維護標準。文章主張建立歐洲多中心 pilot，以形成 IAQ-U 評估指引，並可能降低 airborne HAIs 與強化 pandemic preparedness，但摘要未提供具體感染率或成本效益數字。
- Limitation：敘述性回顧與 opinion paper 本質上容易受文獻選擇與作者判斷影響，未見系統性檢索、RoB 評估或 pooled effect。空氣品質指標與 HAIs 之間的因果鏈也可能受建築設計、病人流動、診斷偵測與感染管制措施混雜。
- Bottom line：對 transplant／血液病照護而言，病房外與檢查區等 unprotected hospital areas 的空氣品質應被納入感染管制與 preparedness 討論。
One Health implementation for rabies elimination in India by 2030: Progress, governance, challenges, and policy alignment¶
One Health | IF 5.7 | DOI | PMID 42494549
- 設計：這是針對印度 2030 年消除犬媒介人類 rabies 目標的政策評論，置於 National Action Plan for Rabies Elimination 與全球 Zero by 30 框架下。文章使用 2022–2023 年全國代表性資料作為問題背景。
- 樣本：不適用傳統樣本數；討論對象是印度全國 dog-bite 暴露、人類 rabies 死亡、犬隻疫苗、PEP／PrEP 可近性與跨部門治理。摘要指出 dog-bite exposure 與可預防死亡仍持續，但未提供具體人數、發生率或地區分層數字。
- 關鍵論點：主要論點是印度進展緩慢並非缺乏有效預防工具，而是 implementation gaps：governance 分散、整合 surveillance 弱、犬隻疫苗覆蓋不足、PEP 可近性不均，以及 multisectoral accountability 不足。作者主張 operational One Health systems、mass dog vaccination、universal intradermal PEP 與高風險低可近性地區的 targeted PrEP。
- Limitation：這是 commentary，不是介入研究或正式政策評估，因此不能量化各治理缺口對 rabies 死亡的相對貢獻。摘要也未提供犬隻疫苗覆蓋、PEP 延遲或死亡下降幅度等數字，臨床與公衛推論主要依賴政策邏輯與既有防治共識。
- Bottom line：rabies 消除的瓶頸在 One Health 執行系統，而不只是醫療端 PEP；治理、犬隻疫苗與 surveillance 必須一起補上。
🔴 Transplant & Opportunistic Infections¶
Investigation of Donor-Transmitted Strongyloides stercoralis Infections in Solid Organ Transplant Recipients, United States, 2012-2024¶
Authors: Pereira MR | Journal: Am J Transplant | Date: 2026 Jul 23
DOI: 10.1016/j.ajt.2026.07.027 | PMID: 42492639
TL;DR: 美國2012–2024年64起疑似donor-derived Strongyloides stercoralis調查中，197名SOT recipients有21例證實感染、來自15名未篩檢donors，且3例死亡直接歸因於strongyloidiasis；31名篩檢陽性donors的77名recipients接受ivermectin prophylaxis後無人發病，支持universal donor screening加上快速通知與預防治療。（全文補摘要 — 機構訂閱全文）
Machine learning for early screening of influenza A-associated invasive pulmonary aspergillosis in hospitalized patients: a real-world study¶
Authors: Wang Y et al. | Journal: Front Cell Infect Microbiol | Date: 2026
DOI: 10.3389/fcimb.2026.1896920 | PMID: 42494852
TL;DR: 234名住院 influenza A 患者中59例 IAPA；LightGBM 以常規臨床資料早期篩檢，validation AUC 0.800、sensitivity 0.76、specificity 0.69。
嘻嘻：LightGBM來顧肺，至少夜班少一點通靈。
Growth, infection, and humoral immunity in children who are HIV exposed and uninfected¶
Authors: Djounda R et al. | Journal: Front Cell Infect Microbiol | Date: 2026
DOI: 10.3389/fcimb.2026.1816838 | PMID: 42494849
TL;DR: 追蹤210名孕婦所生嬰兒12個月，HEU與HUU整體生長、感染與抗體變化相近；男嬰HEU在3與12個月stunting較高，且rhinorrhea風險增加。
不嘻嘻：HEU男嬰的小小警訊，追蹤表又多一格。
Biomarker-driven strategy for early discontinuation of empirical antifungal treatment in critically ill patients: the role of (1-3)-β-D-glucan using Wako® test¶
Authors: Albanell-Fernández M et al. | Journal: J Antimicrob Chemother | Date: 2026 Jul 02
DOI: 10.1093/jac/dkag226 | PMID: 42497386
TL;DR: 90名重症經驗性echinocandin治療患者中，Wako® BDG陰性者早停率77.2% vs 19.2%，總antifungal療程3 vs 8天，未增加30天IC或死亡。
嘻嘻：BDG陰性敢收手，antifungal steward笑了。
Research trends in COPD-associated invasive pulmonary aspergillosis over the past two decades: a bibliometric and topic modelling analysis¶
Authors: Wu X et al. | Journal: Eur J Clin Microbiol Infect Dis | Date: 2026 Jul 24
DOI: 10.1007/s10096-026-05600-7 | PMID: 42496834
TL;DR: 2003–2025年COPD-associated IPA文獻共288篇、60國參與，核心主題集中於epidemiology、risk factors、ICU、diagnosis與treatment。
不嘻嘻：COPD合併IPA，二十年後還在找出口。
Epidemiology, Clinical Features, and Outcomes of Proven Invasive Fungal Infections in Pediatric Patients¶
Authors: Yıldız Sametoğlu S et al. | Journal: Mycopathologia | Date: 2026 Jul 24
DOI: 10.1007/s11046-026-01094-1 | PMID: 42496763
TL;DR: 65名免疫低下兒童proven IFI中yeast占67.7%、mold占32.3%；整體死亡率36.9%，mechanical ventilation為IFI-attributable mortality唯一獨立因子，OR 14.5。
不嘻嘻：兒童IFI還是硬仗，呼吸器一上就很沉重。
Clinical and microbiological epidemiology of Candida infections in a high-complexity hospital in Tolima, Colombia (2014-2024)¶
Authors: Ramírez-Trujillo RA et al. | Journal: PLoS One | Date: 2026
DOI: 10.1371/journal.pone.0354684 | PMID: 42497227
TL;DR: 哥倫比亞Tolima醫院2014–2024年987例candidiasis中candidemia占2.0%；Candida albicans最常見58.9%，device、手術與tumor與candidemia相關。
不嘻嘻：Candida很老派，但device永遠很會幫忙。
The news media and the agenda for noncommunicable diseases before and during the COVID-19 pandemic: Losing the competition for coverage and framing responsibility for action in Malawi¶
Authors: Hamunakwadi DL et al. | Journal: PLoS One | Date: 2026
DOI: 10.1371/journal.pone.0341285 | PMID: 42497109
TL;DR: 馬拉威2015–2023年兩家媒體標題顯示NCD能見度長期低於HIV/AIDS、TB與malaria；COVID-19期間mental health報導上升，但責任框架少指向政府。
不嘻嘻：NCD搶不過感染症版面，公共衛生也有流量焦慮。
Developing an integrated medication event monitoring system and smartphone-based ecological momentary assessment delivery platform to identify real-time factors influencing TB treatment adherence in South Africa¶
Authors: Jimah T et al. | Journal: J Clin Tuberc Other Mycobact Dis | Date: 2026 Aug
DOI: 10.1016/j.jctube.2026.100636 | PMID: 42495709
TL;DR: 南非10名新診斷drug-susceptible TB成人試用MEMS-mEMA兩個月，MEM裝置開啟中位61天；平台可即時收集服藥與影響adherence因素。
嘻嘻：TB服藥終於有即時線索，不只靠問「有吃嗎」。
Cutaneous Mycobacterium haemophilum Infection in an Immunosuppressed Host: A Case Report of Diagnostic Considerations and Microbiologic Confirmation¶
Authors: Lane A et al. | Journal: Clin Case Rep | Date: 2026 Jul
DOI: 10.1002/ccr3.73131 | PMID: 42495431
TL;DR: 免疫抑制宿主皮膚Mycobacterium haemophilum感染易因需鐵補充與低溫培養而漏診；早期考慮NTM並使用molecular diagnostics有助確認，IRIS可模擬惡化。
不嘻嘻：M. haemophilum很挑培養，診斷也很挑耐心。
Hiding in Plain Sight: A Case of Intestinal Tuberculosis Masquerading as Benign Lower GI Bleeding¶
Authors: Otom L et al. | Journal: Case Rep Gastrointest Med | Date: 2026
DOI: 10.1155/crgm/7499395 | PMID: 42494472
TL;DR: 新診斷advanced HIV、CD4 55 cells/mm3患者以6個月腹瀉與間歇hematochezia表現，重複切片見caseating granulomas與acid-fast bacilli後確診intestinal TB。
不嘻嘻：intestinal TB又變裝登場，腸胃科先被考倒。
High Burden of Invasive Fungal Infection in Korean Pediatric Liver Transplant Recipients: A Single-Center Retrospective Cohort Study (2012-2023)¶
Authors: Lee JY et al. | Journal: Yonsei Med J | Date: 2026 Aug
DOI: 10.3349/ymj.2025.0348 | PMID: 42494267
TL;DR: 韓國115名兒童126次liver transplant中，90天IFI粗發生率19.0%，95.4%為invasive candidiasis；IFI組1年存活率58.4% vs 82.8%。
不嘻嘻：移植後真菌一來，兒科團隊血壓先升高。
Drivers of sex differences in Mycobacterium tuberculosis immunoreactivity among adolescents and adults in Blantyre, Malawi¶
Authors: Phiri MD et al. | Journal: BMC Glob Public Health | Date: 2026 Jul 23
DOI: 10.1186/s44263-026-00302-w | PMID: 42493803
TL;DR: 馬拉威布蘭岱2833名10–40歲受試者Mtb immunoreactivity為17.8%；20–29歲男性26.3%高於女性17.7%，tobacco與alcohol與陽性相關。
不嘻嘻：Mtb跟菸酒交朋友，公衛人員又要嘆氣。
The Assessment of Air Quality in Unprotected Hospital Areas: An Opinion Paper¶
Authors: D'Elia D et al. | Journal: J Hosp Infect | Date: 2026 Jul 23
DOI: 10.1016/j.jhin.2026.07.016 | PMID: 42492844
TL;DR: 2015–2025年IAQ-U敘述性回顧指出，醫院非protected區域缺乏一致空氣品質建議；作者主張ESCMID協調歐洲多中心pilot以建立評估指引。
不嘻嘻：醫院空氣也需要指南，不然只能靠感覺流。
Investigating the role of baseline gut Akkermansia muciniphila and its co-metabolite palmitoleic acid in BCG vaccine efficacy: a preclinical study¶
Authors: Chen D et al. | Journal: EBioMedicine | Date: 2026 Jul 23
DOI: 10.1016/j.ebiom.2026.106404 | PMID: 42492179
TL;DR: 小鼠multi-omics顯示接種前腸道Akkermansia muciniphila較高會削弱BCG保護；其co-metabolite palmitoleic acid透過MptpB與actin cytoskeleton路徑抑制反應。
不嘻嘻：連腸道菌都能扯BCG後腿，免疫學真會加戲。
🟢 One Health / Zoonoses¶
Seminal fluid enhances monkeypox virus infection via amyloidogenic fibrils¶
Authors: Torbica E et al. | Journal: Emerg Microbes Infect | Date: 2026 Dec
DOI: 10.1080/22221751.2026.2703396 | PMID: 42497353
TL;DR: Human seminal fluid可大幅增強MPXV感染primary fibroblasts、keratinocytes、monocytes與ex vivo skin；SEVI/SEM amyloid fibrils增加attachment與uptake，CLR01可阻斷。
不嘻嘻：MPXV遇到精液加成，性傳播劇本更難看。
Southern Tick-Associated Rash Illness in Pediatric Patient, New York, USA, 2025¶
Authors: Handel AS et al. | Journal: Emerg Infect Dis | Date: 2026 Jul 24
DOI: 10.3201/eid3209.260871 | PMID: 42497065
TL;DR: 2025年美國紐約兒童於Amblyomma americanum叮咬後發生STARI樣皮疹，tick中檢出具爭議病因角色的Borrelia lonestari。
不嘻嘻：tick咬一下也能開懸案，皮膚科不孤單。
One Health implementation for rabies elimination in India by 2030: Progress, governance, challenges, and policy alignment¶
Authors: Phukan P | Journal: One Health | Date: 2026 Dec
DOI: 10.1016/j.onehlt.2026.101520 | PMID: 42494549
TL;DR: 印度雖以2030年消除犬媒介人類rabies為目標，2022–23全國資料仍顯示dog-bite暴露與可預防死亡持續；瓶頸在governance、surveillance、犬隻疫苗與PEP可近性。
不嘻嘻：rabies明明可防，系統卡關最讓人無力。
When silos cannot be broken: Rethinking integration and coexistence in one health¶
Authors: Fernandes JB | Journal: One Health | Date: 2026 Dec
DOI: 10.1016/j.onehlt.2026.101522 | PMID: 42494547
TL;DR: One Health不宜只追求打破silos；silos也保存專業、問責與制度連貫性，重點應是建立technical、relational與governance bridges以支持協作。
嘻嘻：silos不用全拆，會搭橋才是真本事。
LncRNA ckATP1A1-AS1 inhibits influenza A virus replication by mediating innate immune responses and suppressing viral nuclear import¶
Authors: Fan M et al. | Journal: J Virol | Date: 2026 Jul 24
DOI: 10.1128/jvi.00259-26 | PMID: 42496117
TL;DR: ckATP1A1-AS1為IAV誘導的抗病毒lncRNA，可上調interferon-β與ISGs，並直接結合viral nucleoprotein、阻斷importin α5與核輸入，抑制多種IAV複製。
嘻嘻：lncRNA親自擋IAV進核，細胞也會守門。
Identification of TMEM41B TM6 as a critical domain for coronavirus replication in vitro and in vivo¶
Authors: Fang P et al. | Journal: J Virol | Date: 2026 Jul 24
DOI: 10.1128/jvi.00493-26 | PMID: 42496115
TL;DR: TMEM41B TM6 domain為PDCoV與其他coronavirus複製所需；CRISPR刪除小鼠TM6可降低MHV感染與肝損傷，並提高感染後存活率。
嘻嘻：TMEM41B被抓到要害，coronavirus少一張牌。
Serology and PCR for Apicomplexa and SARS-CoV-2 in feral cats from a Brazilian island¶
Authors: de Matos ER et al. | Journal: Ecohealth | Date: 2026 Jul 24
DOI: 10.1007/s10393-026-01811-8 | PMID: 42496817
TL;DR: 巴西里約熱內盧Furtada Island 52隻feral cats中，40.4%有Toxoplasma gondii暴露、13.7%有Sarcocystis spp.暴露；未檢出SARS-CoV-2血清陽性或組織DNA。
不嘻嘻：野貓沒有SARS-CoV-2，倒是寄生蟲很有存在感。
Salmonella-specific phages from captive bearded dragons (Pogona vitticeps): Temperate traits and temperature-dependent variability in inhibition across isolates¶
Authors: Küper K et al. | Journal: J Appl Microbiol | Date: 2026 Jul 24
DOI: 10.1093/jambio/lxag188 | PMID: 42496608
TL;DR: 18份bearded dragon糞便分離出17株S. enterica-specific phages；對41株S. enterica最高感染63.4%，37°C抑制較明顯，但全為temperate phages限制直接治療用途。
不嘻嘻：phage很會打S. enterica，但temperate先扣分。
Genotype constellations and segment-specific phylogenetic incongruence in bovine rotavirus A associated with fatal neonatal calf diarrhoea in Türkiye¶
Authors: Oz ME et al. | Journal: Microb Pathog | Date: 2026 Jul 23
DOI: 10.1016/j.micpath.2026.108728 | PMID: 42492859
TL;DR: 土耳其fatal neonatal calf diarrhoea RVA株呈G6-P[1]-I2與G8-P[1]-I2，VP7與VP4/VP6 phylogeny不一致支持reassortment；病理變化未隨genotype不同。
不嘻嘻：rotavirus重配牌，牛犢腹瀉還是很兇。
Molecular detection of Coxiella spp. and characterization of blood-feeding sources in tick species parasitizing domestic animals in cattle farms from Magdalena Medio, Colombia¶
Authors: Cabrera R et al. | Journal: Vet Microbiol | Date: 2026 Jul 21
DOI: 10.1016/j.vetmic.2026.111156 | PMID: 42492119
TL;DR: 哥倫比亞Magdalena Medio兩牧場檢出Coxiella spp.：宿主10.5%、ticks 1.36%；16S rRNA/rpoB顯示C. burnetii與Coxiella-like endosymbionts並存。
不嘻嘻：Coxiella在牧場低調出沒，ticks很會藏線索。
Prebiotics and probiotics in animal nutrition: implications for food safety, sustainability, and circular production systems¶
Authors: Dos Anjos Almeida JV et al. | Journal: Braz J Microbiol | Date: 2026 Jul 24
DOI: 10.1007/s42770-026-02033-4 | PMID: 42496792
TL;DR: Prebiotics/probiotics可改善畜禽水產生長、feed conversion與腸道屏障，並抑制E. coli、Salmonella、Vibrio等pathogens；有助降低antimicrobial依賴。
嘻嘻：腸道菌顧好一點，抗生素依賴就少一點。
Chitosan as a sustainable decontamination strategy against Salmonella and Listeria monocytogenes on pig carcass surfaces: Comparative efficacy with organic acids¶
Authors: Ciríaco M et al. | Journal: Vet World | Date: 2026 Jun
DOI: 10.14202/vetworld.2026.2554-2567 | PMID: 42494687
TL;DR: 豬皮25 cm²接種5–6 log CFU/cm²後，0.5% chitosan對Salmonella Typhimurium 48小時降低1.46 log，終點較control低2.68 log，效果優於lactic/citric acid。
嘻嘻：chitosan刷豬皮，食安也可以走永續路線。
🟡 Food Security / Food Safety¶
Sulfur Dioxide in Food: A Review of Its Preservative Mechanisms, Safety Concerns, and the Rise of Smart Detection Systems¶
Authors: Ren J et al. | Journal: Compr Rev Food Sci Food Saf | Date: 2026 Jul
DOI: 10.1111/1541-4337.70580 | PMID: 42494156
TL;DR: SO2仍是重要食品preservative，但多種化學型態、動態釋放與包裝headspace分布不均使即時監測困難；smart sensors與active packaging可改善殘留控制。
不嘻嘻：SO2很好用也很難管，食品監測沒有輕鬆局。
Integration of nontargeted screening with in vitro bioassays to evaluate and identify estrogenic compounds in food contact materials¶
Authors: Li H et al. | Journal: Food Chem | Date: 2026 Jul 17
DOI: 10.1016/j.foodchem.2026.150469 | PMID: 42492282
TL;DR: 29種food-contact materials遷移液中逾半可能具estrogenic effects；GC-Orbitrap-HRMS辨識9種風險物質，silicone水杯化學物貢獻總效應86.5%。
不嘻嘻：水杯都能有estrogenic drama，日用品很會加戲。
Harnessing the pyrophosphate-triggered disassembly of MIL-88B(Fe) for in situ dual-signal generation and reliable acetamiprid detection¶
Authors: Zhao B et al. | Journal: Food Chem | Date: 2026 Jul 19
DOI: 10.1016/j.foodchem.2026.150488 | PMID: 42492278
TL;DR: 智慧型手機整合fluorescence/colorimetric雙模式平台偵測acetamiprid，detection limits為41.0與45.0 pg/mL；蔬果萃取液驗證具高specificity與現場應用潛力。
嘻嘻：手機偵測農藥，現場篩檢越來越像科幻。
The high-stable index as an approach to reveal the potential planting area for winter wheat¶
Authors: Sun H et al. | Journal: J Sci Food Agric | Date: 2026 Jul 23
DOI: 10.1002/jsfa.70923 | PMID: 42493852
TL;DR: 中國冬小麥HSI評估顯示傳統種植區中高度適合21.8%、中度適合37.6%；1999–2019年仍有約81.7×10^6 ha適合土地未種植。
嘻嘻：小麥地圖畫得更細，糧食規劃少點猜拳。
Prevalence and associated factors of depression, anxiety, and stress among flood-affected women in Bangladesh: a case study following 2024 flash flood¶
Authors: Al Hattawi KS et al. | Journal: Front Public Health | Date: 2026
DOI: 10.3389/fpubh.2026.1830406 | PMID: 42494895
TL;DR: 孟加拉Feni 2024 flash flood後504名受災女性中，severe depression 71.1%、anxiety 48.8%、stress 60.6%；收入活動、社會支持與安全飲水與較低distress相關。
不嘻嘻：洪災後心理負擔爆表，災後照護不能只修屋頂。
Short-term cold acclimation influences Rhyzopertha dominica (Coleoptera: Bostrichidae) mobility in different temperatures¶
Authors: Christensen DE et al. | Journal: J Insect Sci | Date: 2026 Jul 01
DOI: 10.1093/jisesa/ieag072 | PMID: 42497447
TL;DR: Rhyzopertha dominica短期18°C acclimation後，在10°C移動距離增加、immobile events減少；但20與30°C反而活動下降，效果受sex與strain調節。
不嘻嘻：害蟲冷一下更會跑，倉儲管理又被出題。
Recurrent evolution of cryptic triploids in cultivated enset increases yield¶
Authors: Dussert Y et al. | Journal: PLoS Genet | Date: 2026 Jul 24
DOI: 10.1371/journal.pgen.1012241 | PMID: 42497221
TL;DR: 723個野生與栽培enset樣本顯示約20%栽培clones為triploid，且多次獨立演化；triploid clone種植較頻繁，平均pseudostem volume高於diploid。
嘻嘻：triploid enset默默增產，作物演化很懂實用主義。
Insights into the genomic features of the emerging pathogens Cronobacter malonaticus and Cronobacter turicensis¶
Authors: Vilela FP et al. | Journal: Folia Microbiol (Praha) | Date: 2026 Jul 24
DOI: 10.1007/s12223-026-01561-8 | PMID: 42496941
TL;DR: 全球104株Cronobacter malonaticus與89株C. turicensis genome分析顯示高種內多樣性；C. turicensis全帶fos，兩者皆普遍具71個virulence genes。
不嘻嘻：Cronobacter基因很精彩，嬰幼兒食品先緊張。
A review of ultrasonic pasteurization in milk and milk-based beverages using different ultrasound systems and thermal conditions: from mechanistic insights to regulatory challenges¶
Authors: Yu R et al. | Journal: Food Sci Anim Resour | Date: 2026 Jul 24
DOI: 10.1007/s44463-026-00105-5 | PMID: 42496922
TL;DR: 超音波pasteurization在牛奶與乳飲中可藉acoustic cavitation滅活microbes，但效果高度受系統設計、processing mode與熱效應影響；工業化仍需法規與製程最佳化。
嘻嘻：超音波殺菌有戲，但工廠端還要慢慢磨。
Heterologous Systems in the Functional Characterization of Proteins from Phytopathogenic Fungi: A Systematic Review¶
Authors: de Oliveira HVV et al. | Journal: Mol Biotechnol | Date: 2026 Jul 24
DOI: 10.1007/s12033-026-01592-z | PMID: 42496915
TL;DR: PRISMA系統性回顧122篇fungal phytopathogen protein實驗，heterologous hosts以E. coli、Saccharomyces cerevisiae、Pichia pastoris與Nicotiana benthamiana為主。
嘻嘻：真菌蛋白換宿主表演，工具箱越來越齊。
資料來源：PubMed (articles retrieved 2026-07-25)