Daily Journal Digest — 2026-08-31¶
過去 24 小時新增：Transplant ID × 3、One Health × 10、Food Security × 11，共 24 篇。
🔴 Transplant & Opportunistic Infections¶
Influenza A-Associated Pulmonary Aspergillosis in Critically Ill Patients in the Post-COVID-19 Era: A Multicenter Cohort Study from China¶
Authors: Xue M et al. | Journal: Int J Infect Dis | Date: 2026 Aug 29
DOI: 10.1016/j.ijid.2026.109089 | PMID: 42668058
TL;DR: 中國 21 ICU 542 名 severe Influenza A pneumonia 中，IPA 佔 33.0%，60 天死亡率 47.5% vs 32.0%；glucocorticoids、diabetes、RRT 與 bacterial co-infection 為獨立風險因子。
不嘻嘻：flu season 一到，Aspergillus 也來加班。
Social determinants of abdominal tuberculosis severity: An experience from a large tertiary care center¶
Authors: Samad A et al. | Journal: Pak J Med Sci | Date: 2026 Aug
DOI: 10.12669/pjms.42.8.15840 | PMID: 42668912
TL;DR: 卡拉奇 503 名 intestinal tuberculosis 患者中，重症佔 29.4%；diabetes、malnutrition、addiction 類型與地理位置和嚴重度相關，HIV、性別與社經狀態未達顯著。
不嘻嘻：tuberculosis 從來不只考驗藥物，也考驗人生。
Clinical practice guideline for psoriasis management in Latin America¶
Authors: Valenzuela F et al. | Journal: An Bras Dermatol | Date: 2026 Aug 29
DOI: 10.1016/j.abd.2026.501449 | PMID: 42667799
TL;DR: 拉丁美洲 psoriasis guideline 以 GRADE 制定治療目標，建議 methotrexate、cyclosporine、acitretin、phototherapy 為第一線，並規範 biologics、小分子與特殊族群處置。
嘻嘻：guideline 願意好好在地化，就是臨床福音。
🟢 One Health / Zoonoses¶
From buffalo to human: Klebsiella pneumoniae in high-somatic cell count milk as an overlooked link in the one health chain¶
Authors: Wei Z et al. | Journal: Int J Food Microbiol | Date: 2026 Aug 26
DOI: 10.1016/j.ijfoodmicro.2026.112027 | PMID: 42667764
TL;DR: 中國廣西 high-SCC 水牛奶 460 個 isolates 中檢出 23 株 Klebsiella pneumoniae（5.0%），78.26% 與人類參考株高度相似；ST37、K1、yersiniabactin 與 MDR 表型提示 One Health 風險。
不嘻嘻：牛奶鏈也能藏 Klebsiella，早餐突然沉重。
Genomic epidemiology reveals agricultural environments as direct conduits for multidrug-resistant Salmonella ST34 transmission into the food chain¶
Authors: Liao N et al. | Journal: Food Microbiol | Date: 2027 Jan
DOI: 10.1016/j.fm.2026.105224 | PMID: 42668214
TL;DR: 中國江西 237 株 Salmonella isolates 顯示 ST34（72.4% MDR）主導都市食物與臨床來源，農業廢水與臨床株僅差 2–10 core genome SNPs，鄉村 contaminated irrigation water 年感染風險高 139 倍。
不嘻嘻：Salmonella 搭灌溉水進城，One Health 又警鈴大作。
Genomic insights into Salmonella enterica serovar Corvallis from China 2014-2023: A foodborne bacterial pathogen for antimicrobial resistance carriage and potential global transmission¶
Authors: Yan S et al. | Journal: Food Microbiol | Date: 2027 Jan
DOI: 10.1016/j.fm.2026.105236 | PMID: 42668177
TL;DR: 2014–2023 中國 260 株 S. Corvallis 合併全球 598 genomes 顯示 ST1541 為主，雞肉鏈 ARGs 較多人源株多；≤10 SNP clusters 與 UK-中國連結支持跨區傳播及 MGE 驅動 AMR 擴散。
不嘻嘻：S. Corvallis 跟著雞肉旅行，護照還附 ARGs。
Farm management factors associated with antimicrobial resistance in dairy herds: Insights from a bulk tank milk study¶
Authors: Kovandžić M et al. | Journal: Food Microbiol | Date: 2027 Jan
DOI: 10.1016/j.fm.2026.105228 | PMID: 42668175
TL;DR: 塞爾維亞 100 個乳牛場 bulk tank milk 中，MRSA 5 場、ESBL E. coli 4 場，未檢出 VRE、CPE、ColR-E；多數 confirmed isolates 為 MDR，較高單牛日產乳量與 ESBL E. coli 相關。
不嘻嘻：連 bulk milk 都在提醒我們抗生素帳要算清楚。
Multidrug-resistant and virulent Streptococcus suis strains detected in clinically healthy pigs in Guangdong and Guangxi, China¶
Authors: Peng Z et al. | Journal: Vet Res | Date: 2026 Aug 29
DOI: 10.1186/s13567-026-01832-9 | PMID: 42668373
TL;DR: 廣東與廣西健康豬 315 株 Streptococcus suis 中，96.82% 為 MDR、29.84% 對 penicillin resistant，40.63% cps types 與人類感染相關；ICEs 與 prophages 可能促進 virulence determinants 擴散。
不嘻嘻：健康豬身上的 S. suis，比履歷還精彩。
Genomic characterization and pathogenicity of ruminant Listeria monocytogenes isolates in a murine oral infection model¶
Authors: Kim J et al. | Journal: Vet Microbiol | Date: 2026 Aug 25
DOI: 10.1016/j.vetmic.2026.111203 | PMID: 42667904
TL;DR: 反芻動物 Listeria monocytogenes oral mouse model 中，LM18（serotype 1/2b, ST224, SL6178）致死劑量最低且造成肺部 secondary bacteremia；SSI-1 可能提升胃腸道存活與 virulence。
不嘻嘻：Listeria 的動物版劇本，照樣能演成重症片。
Genomic analysis of Escherichia coli, Enterobacter hormaechei, and Cupriavidus gilardii isolated from Cacatua alba¶
Authors: de Andrade JP et al. | Journal: Vet Res Commun | Date: 2026 Aug 29
DOI: 10.1007/s11259-026-11490-z | PMID: 42667506
TL;DR: 圈養 Cacatua alba 肺與腦分離出 MDR E. coli、Enterobacter hormaechei、Cupriavidus gilardii；AV037/AV038 保留 carbapenem susceptibility，AV039 對 meropenem resistant 且接近環境與人源 strains。
不嘻嘻：鸚鵡病原也懂 MDR，寵物醫學壓力山大。
Distinct Tissue Localization and Transcriptional Profiles of Shiga Toxin-Producing Escherichia coli With and Without the Locus of Enterocyte Effacement at the Bovine Recto-Anal Junction¶
Authors: Méndez D et al. | Journal: Int J Microbiol | Date: 2026
DOI: 10.1155/ijm/2576911 | PMID: 42668840
TL;DR: 牛 recto-anal junction model 顯示 LEE-positive STEC（O157:H7、O26:H11）可延伸至表層以外上皮，LEE-negative strains 多侷限表層；eae、iha、csgD、pgaA 與 saa 表現支持不同 colonization 策略。
嘻嘻：STEC 的黏附地圖越清楚，防堵才有方向。
ITS-based metabarcoding of broiler and layer chicken litter: Linking fungal diversity to environmental and One Health risks¶
Authors: Corrêa-Junior D et al. | Journal: Fungal Biol | Date: 2026 Oct
DOI: 10.1016/j.funbio.2026.101807 | PMID: 42668153
TL;DR: 三座商業 poultry houses 的 ITS metabarcoding 顯示 ITS1 比 ITS2 偵測更高 fungal richness，且各場菌相不同；檢出 Aspergillus、Trichosporon、Microascus 等臨床相關 genera，支持 One Health biosecurity 監測。
不嘻嘻：雞舍灰塵裡的 fungal cast，陣容有點豪華。
Climate-sensitive infectious diseases in the context of climate change: Lessons from Brazil's floods, with leptospirosis as an example¶
Authors: Sansone NMS et al. | Journal: Infect Dis Now | Date: 2026 Aug 29
DOI: 10.1016/j.idnow.2026.105347 | PMID: 42668137
TL;DR: 巴西 2014–2024 年通報 36,261 例 leptospirosis、3,170 死；2024 年全國病例 4,142、死亡 362，南部增幅最大，南里奧格蘭德洪災期間有 242 confirmed cases、17 deaths。
不嘻嘻：氣候變遷把 leptospirosis 變成災後固定班底。
🟡 Food Security / Food Safety¶
An integrated litmus test platform for low-background detection and photothermal inactivation of Salmonella typhimurium via HCR-urease signal amplification¶
Authors: Kang Q et al. | Journal: Food Chem | Date: 2026 Aug 27
DOI: 10.1016/j.foodchem.2026.150935 | PMID: 42667770
TL;DR: HCR-urease litmus platform 偵測 Salmonella typhimurium 達 2.34 CFU/mL detection limit，肉眼判讀可至 10^3 CFU/mL；808 nm NIR photothermal 處理可降低 viability，spiked food recovery 84.2%–115.3%。
嘻嘻：試紙加光熱殺菌，Salmonella typhimurium 有點失策。
Risk prioritization of household food handling practices in China: a fuzzy failure mode and effect analysis¶
Authors: Zhang S et al. | Journal: Food Microbiol | Date: 2027 Jan
DOI: 10.1016/j.fm.2026.105263 | PMID: 42668200
TL;DR: 中國 household food handling Fuzzy-FMEA 顯示，生熟食未分刀板風險排序最高；reheating 不足與 improper food storage 也應優先介入，可作為家戶 food safety 管理與衛教排序工具。
嘻嘻：家戶食安終於有排序工具，不再只靠碎念。
Genomic sequencing reveals htpX is a novel spoilage factor from foodborne pathogen Aeromonas veronii: Insights into extracellular enzymes, biofilm formation, stress tolerance, virulence and spoilage¶
Authors: Tang X et al. | Journal: Food Microbiol | Date: 2027 Jan
DOI: 10.1016/j.fm.2026.105260 | PMID: 42668197
TL;DR: 食源性 A. veronii GL2 中 htpX 在熱處理後上調；ΔhtpX 的 LD50 較野生株高 18.5 倍，biofilm、hemolysis、stress tolerance、致病與腐敗能力均下降。
嘻嘻：找到 htpX，食品安全又多一個可瞄準的弱點。
Chlorine dioxide injures Shigella flexneri, weakens biofilms, and produces a VBNC-like phenotype under cold stress: matrix-limited efficacy in broccoli wash water¶
Authors: Li Y et al. | Journal: Food Microbiol | Date: 2027 Jan
DOI: 10.1016/j.fm.2026.105258 | PMID: 42668195
TL;DR: ClO2 對 S. flexneri 的 MIC/MBC 為 200/400 mg/L，可造成 envelope、氧化與能量傷害並削弱 biofilm；4°C 加 sub-MIC ClO2 會誘導 VBNC-like persistence。
不嘻嘻：冷藏加消毒還躲起來，Shigella 很會裝死。
Molecular mechanisms of the VBNC state induced by polyhexamethylene guanidine in biofilm-associated Staphylococcusaureus¶
Authors: Zeng S et al. | Journal: Food Microbiol | Date: 2027 Jan
DOI: 10.1016/j.fm.2026.105257 | PMID: 42668194
TL;DR: 0.4% PHMG 3 小時內消除 biofilm-associated Staphylococcus aureus 可培養性，但 25°C TSB biofilm 仍有 25.70±3.83% viable fraction；轉入牛奶後 4 小時內 resuscitate 並恢復 hemolysin。
不嘻嘻：S. aureus 泡完牛奶復活，食品微生物真的很難下班。
Cinnamon essential oil synergizes with sodium hypochlorite to suppress VBNC formation in Escherichia coli O157:H7 by modulating the temporal expression of arcA/relA-associated stress regulators¶
Authors: Zhao H et al. | Journal: Food Microbiol | Date: 2027 Jan
DOI: 10.1016/j.fm.2026.105256 | PMID: 42668193
TL;DR: cinnamon essential oil 合併 sodium hypochlorite 對 E. coli O157:H7 具 synergy（FICI 0.5），可降低並延後 VBNC 形成，使 arcA/relA 表現下降 2.06–2.13 倍、峰值延後 20 分鐘。
嘻嘻：cinnamon essential oil 意外有戲，廚房香料升級助攻。
FpNuc1α regulates phosphate signaling and pathogenicity in Fusarium proliferatum infection of jujube fruit by targeting FpGit1 via a novel BSN motif¶
Authors: Gao Y et al. | Journal: Food Microbiol | Date: 2027 Jan
DOI: 10.1016/j.fm.2026.105252 | PMID: 42668189
TL;DR: F. proliferatum 的 PHO pathway 影響生長、conidiation 與 stress responses；FpNuc1α 受 phosphate-dependent phosphorylation 控制，透過新 BSN motif 啟動 FpGit1 以維持 full virulence。
嘻嘻：連 phosphate signaling 都能拆出致病開關，真菌學又加戲。
Molecular detection and viability assessment of Toxoplasma gondii in retail dry-cured meat products in the Republic of Korea¶
Authors: Chang T et al. | Journal: Food Microbiol | Date: 2027 Jan
DOI: 10.1016/j.fm.2026.105246 | PMID: 42668183
TL;DR: 韓國市售 451 件 dry-cured meat 中，28 件（6.2%）檢出 T. gondii DNA，美國來源陽性率 17.3%；PCR 陽性樣本 mouse bioassay 均未見 viable parasites，傳播風險可能偏低。
嘻嘻：有 DNA 但沒活蟲，肉乾愛好者暫時鬆一口氣。
Structure-activity relationships and antibacterial membrane disruption of monoterpenoid ketones and lactones¶
Authors: Xie T et al. | Journal: Food Microbiol | Date: 2027 Jan
DOI: 10.1016/j.fm.2026.105244 | PMID: 42668181
TL;DR: D-carvone 與 L-carvone 對 E. coli、S. aureus 活性最強，MIC 0.5 mg/mL、MBC 1.0 mg/mL；主要透過 membrane disruption，造成 protein/核酸外漏、membrane potential 消散與孔洞形成。
嘻嘻：monoterpenoid ketones 打膜路線明確，天然物還有戲。
Genomic diversity, antimicrobial resistance, and virulence profiles of Salmonella from retail pork under different supply modes in Jilin, China¶
Authors: Zheng J et al. | Journal: Food Microbiol | Date: 2027 Jan
DOI: 10.1016/j.fm.2026.105243 | PMID: 42668180
TL;DR: 中國吉林 250 件零售豬肉分離 60 株 Salmonella（24.00%），冷藏供應陽性率高於鮮肉（56.00% vs 20.44%）；61.67% 為 MDR，tetracycline 抗藥率 66.67%，並見 IncHI2/HI2A plasmids 聚集多重 ARGs。
不嘻嘻：豬肉裡 MDR Salmonella 開派對，餐桌壓力山大。
Antimicrobial resistance patterns differ amongst Salmonella enterica recovered from synanthropic flies captured across multiple livestock production systems¶
Authors: Shahanaz E et al. | Journal: Food Microbiol | Date: 2027 Jan
DOI: 10.1016/j.fm.2026.105235 | PMID: 42668176
TL;DR: 德州多種畜牧強度地區蒼蠅樣本中，89/230（38.7%）檢出 Salmonella；分離株對 tetracycline、streptomycin、amoxicillin/clavulanic acid 抗藥率分別為 77.5%、61.8%、56.2%，高畜牧強度郡與 tetracycline AMR 顯著相關。
不嘻嘻：蒼蠅幫 Salmonella 外送 AMR，畜牧場真的不能鬆懈。
資料來源：PubMed (articles retrieved 2026-08-31)