Daily Journal Digest — 2026-07-12¶
過去 24 小時新增：Transplant ID × 16、One Health × 10、Food Security × 11，共 37 篇。
⭐ 今日亮點¶
- Clinical controversies in the management of candidemia in adults and children
candidemia處置進入個人化與診斷 stewardship 時代 - Mapping the global evidence base of bundibugyo ebolavirus disease: a systematic scoping review of research gaps and preparedness priorities
BDBV 是被低估的全球衛生安全缺口 - Controlling foodborne antimicrobial-resistant bacteria: The gen(i)e is out of the bottle
把食物鏈 AMR 從農場用藥擴大到全鏈控管
🔬 深入評讀¶
Clinical controversies in the management of candidemia in adults and children¶
Am J Health Syst Pharm | DOI | PMID 42433186
- 設計：這是成人與兒童 candidemia 管理爭議的敘述性綜述，整合 antifungal dosing、RDT、AFST、echinocandin-to-azole 轉換、療程、眼科與心臟評估、rezafungin、抗藥性與兒童劑量等議題。文章不是系統性回顧，重點在把近年證據轉化成臨床決策框架。
- 樣本：綜述涵蓋 guideline-supported standard care 與近年 emerging evidence，尤其聚焦重症、肥胖、兒童、non-albicans Candida、C. auris 與疑似 metastatic complications 的族群。原文未提供系統性檢索年代、納入研究數或正式 RoB 評估。
- 關鍵論點：核心論點是 candidemia 已不只是「echinocandin 14 天」的固定流程，而是要結合 PK variability、RDT/AFST、早期 species-directed de-escalation 與選擇性 metastatic workup。臨床穩定、血流已 sterilization、且 azole susceptibility 可預測或已確認者，3–5 天後 echinocandin-to-azole transition 看起來安全；truly uncomplicated candidemia 縮短療程有可行訊號，但仍未取代 14 天標準。
- Limitation：主要限制是敘述性綜述未做系統檢索與 pooled effect，許多結論來自異質性 observational data、少量 trial 或 expert interpretation。對 deep-seated infection、Candida endocarditis、rezafungin 長療程應用與兒童 outcome-oriented score 的證據仍不足。
- Bottom line：candidemia 管理應從固定 bundle 走向 RDT/AFST 導向的個人化治療、早期安全降階與選擇性併發症評估。
Mapping the global evidence base of bundibugyo ebolavirus disease: a systematic scoping review of research gaps and preparedness priorities¶
BMC Infect Dis | IF 3.4 | DOI | PMID 42426656
- 設計：這是 systematic scoping review（非原始臨床試驗），依 PRISMA-ScR 搜尋 PubMed/MEDLINE、OpenAlex、Semantic Scholar，涵蓋 2007 年至 2026 年 5 月的全球文獻；主題是 Bundibugyo ebolavirus（BDBV）證據版圖、研究缺口與整備優先順序。
- 樣本：作者自 4,379 筆紀錄篩選出 100 篇高相關研究，但只有 23% 直接處理 BDBV，其餘多為較廣泛 ebolavirus 文獻且以 EBOV 為主；文章另指出 BDBV 既有估計 CFR 約 25%–51%，並以 2026 年 DRC BDBV outbreak 被宣告為 PHEIC 作為背景。
- 關鍵數字：主要發現不是治療效果量，而是證據分布嚴重不均：文獻集中在流行病學驅動因子與臨床特徵，health system response 領域明顯薄弱，且目前沒有 BDBV 已核准 vaccine、specific therapeutic agent，或經驗證的 point-of-care rapid diagnostic test。方法學風險整體為 moderate，缺失 outcome 資料見於 42% 研究、selective reporting 見於 41%，代表結論方向可信但精確度與可轉譯性有限。
- Limitation：最大限制是納入文獻多數並非 BDBV 專屬，只有 23/100 篇直接聚焦 BDBV，容易把 EBOV 主導的知識外推到 BDBV；加上此文為未編修 early-access manuscript，且使用 weighted composite relevance scoring 與概念模型整理證據，較適合描述缺口而非估計因果效應。
- Bottom line：BDBV 的實證基礎仍落後於其 epidemic potential：臨床上不能假設 EBOV 的 vaccine、monoclonal antibody 或診斷工具可直接套用，未來優先事項是 BDBV-specific diagnostics、therapeutics、vaccine validation 與 survivor 長期追蹤。
- GRADE 證據等級：Very low ⊕◯◯◯
Controlling foodborne antimicrobial-resistant bacteria: The gen(i)e is out of the bottle¶
J Food Prot | IF 2.5 | DOI | PMID 42425308
- 設計：這是 antibiotic-resistant bacteria 經食物傳播的敘述性文獻綜述，採 One Health 觀點討論 food 作為環境、人類與動物之間的傳播介面。文章目標是論證「降低農業抗生素使用必要但不充分」，需並行 agrifood stewardship 與全食物鏈 hygiene/contamination control。
- 樣本：原文未提供系統性檢索策略、納入研究數、研究期間或 RoB 評估，因此比較像政策與框架導向的 narrative synthesis。內容涵蓋 animal- and plant-sourced food production、soil、waterway、farm、processing facility、food service 等多個食物鏈節點。
- 關鍵論點：關鍵論點是即使沒有 intentional antibiotic use，食物仍可能在多個階段接觸環境或處理流程中的 antibiotic-resistant bacteria。作者提出兩條互補路徑：AMR-specific interventions 是 agrifood antimicrobial stewardship 以減少抗藥菌 emergence/enrichment；AMR-sensitive interventions 是跨食物鏈衛生與污染控制以降低整體 bacterial loads。
- Limitation：敘述性綜述無 pooled effect，也無法量化各類介入對人類感染、colonization 或 AMR burden 的相對貢獻。不同國家食物系統、監測強度、檢驗方法與暴露型態差異大，框架可轉用但具體優先順序需地方資料支持。
- Bottom line：食物鏈 AMR 控制不能只盯農業抗生素使用，還要把屠宰、加工、流通、餐飲與家庭端污染控制納入 One Health stewardship。
🔴 Transplant & Opportunistic Infections¶
HSCT May Improve Survival in Advanced Extranodal NK/T-Cell Lymphoma: A Single-Center Retrospective Study¶
Authors: Li Z et al. | Journal: Blood Adv | Date: 2026 Jul 10
DOI: 10.1182/bloodadvances.2026020407 | PMID: 42431626
TL;DR: 34例R/R ENKTCL接受allo-HSCT，移植前CR/PR預後較佳；CAEBV、移植後EBV reactivation與較差存活相關，HLH者NRM較高。
嘻嘻：移植這張牌還能打，只是EBV總愛加戲。
Clinical Utility of the Paed-EQUAL Candida Score in Paediatric Candidemia: A Real-World Cohort Study¶
Authors: Aykac K et al. | Journal: Mycoses | Date: 2026 Jul
DOI: 10.1111/myc.70207 | PMID: 42431849
TL;DR: 127名兒童candidemia中30天死亡13.4%、90天21.3%；Paed-EQUAL Candida Score對30天死亡AUC僅0.667，90天無顯著預測力。
不嘻嘻：分數看起來很忙，臨床上卻有點社恐。
Predictors of Cerebral Small-Vessel Disease in Middle-Aged, Virologically Controlled People Living With HIV¶
Authors: Moulignier A et al. | Journal: Open Forum Infect Dis | Date: 2026 Jul
DOI: 10.1093/ofid/ofag382 | PMID: 42434387
TL;DR: 160名病毒控制良好的HIV患者中，CSVD主要與高血壓（OR 4.92）、白血球較高、D-dimer升高及眼壓升高相關，非HIV特異因素。
不嘻嘻：HIV穩了，血管還是被三高追著跑。
Impact of a pharmacist-led infectious disease support team on candidemia bundle adherence and 28-day mortality: a single-center retrospective cohort study¶
Authors: Endo A et al. | Journal: Eur J Clin Microbiol Infect Dis | Date: 2026 Jul 11
DOI: 10.1007/s10096-026-05601-6 | PMID: 42432404
TL;DR: 89例candidemia中，pharmacist-led IDST提升bundle adherence，28天死亡率較低（29.2% vs 56.1%），且獨立降低死亡HR 0.452。
嘻嘻：藥師進場，Candida戰線真的比較有隊形。
Epidemiology and treatment outcomes of TB-HIV co-infection in a rural South African setting: an exploratory analysis of retreatment and contextual factors¶
Authors: Mkono L et al. | Journal: Front Public Health | Date: 2026
DOI: 10.3389/fpubh.2026.1792518 | PMID: 42433412
TL;DR: 南非東開普422名TB患者中TB-HIV共感染率57.8%；HIV狀態未獨立影響治療成功，死亡率與TB-only相近（6.6% vs 10.7%）。
嘻嘻：共病很硬，但治療結局沒有想像中崩盤。
Lauramide-Functionalized Silver-Selenide Nanoparticles Enhance the Therapeutic Efficacy of Pyrimethamine in Murine Reactivated Toxoplasmosis¶
Authors: Al-Ahmadi BM et al. | Journal: Acta Trop | Date: 2026 Jul 10
DOI: 10.1016/j.actatropica.2026.108231 | PMID: 42431569
TL;DR: dexamethasone誘發reactivated toxoplasmosis小鼠中，Lu@AgSe NPs合併低劑量pyrimethamine最能降低parasite burden並改善存活與肝腎指標。
嘻嘻：奈米幫手上線，pyrimethamine突然有隊友。
Accuracy of valganciclovir dosing following kidney transplantation and its impact on clinical outcomes¶
Authors: Forsyth J et al. | Journal: Front Nephrol | Date: 2026
DOI: 10.3389/fneph.2026.1781576 | PMID: 42434437
TL;DR: 90名腎移植接受valganciclovir prophylaxis者，僅51%期間劑量適當；underdosing與CMV DNAemia相關，overdosing與neutropenia相關。
不嘻嘻：valganciclovir劑量像走鋼索，左右都會摔。
Precision myeloablation with TDM-guided busulfan in pediatric primary immunodeficiencies: a real-world study of 28 patients¶
Authors: Zhang K et al. | Journal: Transl Pediatr | Date: 2026 Jun 30
DOI: 10.21037/tp-2026-0344 | PMID: 42433921
TL;DR: 28名兒童PID接受TDM-guided busulfan/Flu allo-HSCT，2年OS與EFS皆96.42%；首劑達標僅39.3%，凸顯TDM必要性。
嘻嘻：busulfan有TDM導航，兒童PID移植很亮眼。
Occurrence of drug resistance, associated risk factors, and expression of cytokine IL-33 in human TB patients¶
Authors: Aslam S et al. | Journal: Ann Med Surg (Lond) | Date: 2026 Jul
DOI: 10.1097/MS9.0000000000005169 | PMID: 42433842
TL;DR: 82例Gene Xpert陽性pleural TB中16例rifampicin resistant；IL-33於患者血清與胸水升高，合併HIV、糖尿病等共病者更明顯。
不嘻嘻：rifampicin resistant TB又來提醒我們別太樂觀。
Clinical controversies in the management of candidemia in adults and children¶
Authors: Cluck DB et al. | Journal: Am J Health Syst Pharm | Date: 2026 Jul 11
DOI: 10.1093/ajhp/zxag212 | PMID: 42433186
TL;DR: candidemia處置爭議集中於個人化劑量、RDT/AFST、3–5天後echinocandin-to-azole轉換、療程縮短與選擇性眼科/心臟評估。
不嘻嘻：candidemia老問題開會很久，答案還在路上。
Systemic mycobacteriosis caused by Mycobacterium avium subspecies hominissuis in a sheep¶
Authors: Thirumalapura N et al. | Journal: J Vet Diagn Invest | Date: 2026 Jul 11
DOI: 10.1177/10406387261464590 | PMID: 42433111
TL;DR: 羊隻systemic mycobacteriosis個案由Mycobacterium avium subsp. hominissuis造成，WGS發現ISMAP02-like sequence，可能干擾MAP PCR偵測。
不嘻嘻：羊也來示範mycobacteriosis，PCR還順便被整。
Lymphomatous transformation in mass-forming chronic active EBV-associated enteritis initially misdiagnosed as ulcerative colitis: A case report¶
Authors: Yang T et al. | Journal: Medicine (Baltimore) | Date: 2026 Jul 10
DOI: 10.1097/MD.0000000000049616 | PMID: 42432915
TL;DR: 63歲男性chronic active EBV-associated enteritis誤診ulcerative colitis並接受多種biologic therapy，後轉為T-cell lymphoma且快速惡化死亡。
不嘻嘻：EBV腸炎偽裝成IBD，劇情比病歷還狠。
Mucormycosis caused by Rhizopus oryzae, in a patient with diabetes mellitus: a case report¶
Authors: Kolsanov AV et al. | Journal: J Med Case Rep | Date: 2026 Jul 10
DOI: 10.1186/s13256-026-06246-x | PMID: 42432769
TL;DR: 47歲俄羅斯男性新診斷diabetes mellitus與ketoacidosis，發生Rhizopus oryzae rhino-orbito-cerebral mucormycosis，雖手術與治療仍死亡。
不嘻嘻：Rhizopus oryzae一出手，糖尿病真的不能拖。
Incidence, mortality and risk factors of invasive pulmonary aspergillosis in critically ill patients during the COVID-19 era: a global systematic review and meta-analysis¶
Authors: Zhou Z et al. | Journal: Ann Clin Microbiol Antimicrob | Date: 2026 Jul 10
DOI: 10.1186/s12941-026-00878-z | PMID: 42432685
TL;DR: 56研究、15,385名ICU患者meta-analysis顯示IPA pooled incidence 11.9%、死亡率59.6%；mechanical ventilation風險OR 3.69。
不嘻嘻：ICU裡的IPA，死亡率高到讓人想關電腦。
Development of an expert-annotated chest X-ray dataset to support AI validation in tuberculosis diagnosis¶
Authors: Tanomkiat W et al. | Journal: Insights Imaging | Date: 2026 Jul 10
DOI: 10.1186/s13244-026-02334-0 | PMID: 42432306
TL;DR: 1,097張CXR由6名B readers判讀TB，TB一致性κ=0.67、active TB κ=0.76；敏感性77.2–91.1%、特異性87.4–98.6%。
嘻嘻：TB AI驗證有好資料集，模型終於能考真題。
Burden of infectious diseases in a West African tertiary hospital: a two-year retrospective study at CHNU de Fann, Senegal¶
Authors: Sarr A et al. | Journal: J Infect Dev Ctries | Date: 2026 Jun 30
DOI: 10.3855/jidc.22166 | PMID: 42430538
TL;DR: 塞內加爾CHNU de Fann 1,098名感染症住院患者死亡率25.0%；死亡獨立因子含HIV陽性OR 2.1、sepsis OR 2.3與年齡>60歲。
不嘻嘻：感染症病房壓力山大，sepsis仍是硬仗。
🟢 One Health / Zoonoses¶
Surveillance for Coxiella burnetii animal reservoirs in Hong Kong suggests low zoonotic risk of Q-fever from local animals including ruminants, companion animals and rodents¶
Authors: Rizzo F et al. | Journal: One Health | Date: 2026 Dec
DOI: 10.1016/j.onehlt.2026.101504 | PMID: 42434343
TL;DR: 香港1,118隻動物監測未偵測Coxiella burnetii DNA；僅貓1.3%、山羊0.7%血清陽性，顯示本地動物Q-fever風險低。
嘻嘻：香港Q-fever監測低風險，今天先少一個警報。
Anthrax outbreak associated with the consumption and handling of carcasses of livestock that suddenly died, Kanungu District, Uganda, June-November 2024¶
Authors: Mutesi C et al. | Journal: PLoS Negl Trop Dis | Date: 2026 Jul 10
DOI: 10.1371/journal.pntd.0013727 | PMID: 42430455
TL;DR: 烏干達Kanungu anthrax outbreak共90例、CFR 6.7%；食用暴斃牲畜肉aOR 5.5、處理屍體aOR 8.2為主要感染風險。
不嘻嘻：anthrax再度證明，暴斃牲畜真的別碰。
Co-circulation of Trypanosoma cruzi and Leishmania spp. in Northwestern Colombia, a major migratory corridor¶
Authors: Cantillo-Barraza O et al. | Journal: PLoS Negl Trop Dis | Date: 2026 Jul
DOI: 10.1371/journal.pntd.0014496 | PMID: 42430342
TL;DR: 哥倫比亞Urabá見T. cruzi與Leishmania spp.共同流行：人類T. cruzi感染2.42%，triatomine bugs感染率68.4%，opossum亦有共感染。
不嘻嘻：T. cruzi和Leishmania同台，移民走廊不寂寞。
Mapping the global evidence base of bundibugyo ebolavirus disease: a systematic scoping review of research gaps and preparedness priorities¶
Authors: Boatemaa A et al. | Journal: BMC Infect Dis | Date: 2026 Jul 09
DOI: 10.1186/s12879-026-13977-1 | PMID: 42426656
TL;DR: BDBV scoping review納入100篇高相關研究，僅23%專注BDBV；目前無核准疫苗、特異治療或validated point-of-care rapid diagnostic test。
不嘻嘻：BDBV研究空窗很大，準備度還在補考。
Human exposure to Crimean-Congo hemorrhagic fever virus is associated with livestock management and handling practices in southcentral Tanzania, 2023-2024¶
Authors: Meehan C et al. | Journal: BMC Infect Dis | Date: 2026 Jul 09
DOI: 10.1186/s12879-026-13919-x | PMID: 42426621
TL;DR: 坦尚尼亞中南部850名畜牧社區成人CCHFV IgG盛行率3.41%；屠宰食用病死動物aOR 5.48，私人牧地放牧具保護效果。
不嘻嘻：CCHFV風險藏在牧場日常，刀口下見真章。
First molecular confirmation of Spirometra mansoni (Cestoda: Diphyllobothriidea) in Indonesian cobras (Naja sputatrix and Naja sumatrana)¶
Authors: Edila R et al. | Journal: Parasit Vectors | Date: 2026 Jul 09
DOI: 10.1186/s13071-026-07506-x | PMID: 42426925
TL;DR: 印尼眼鏡蛇15株plerocercoids皆屬Spirometra mansoni，僅2個cox1 haplotypes且跨宿主共享，提示野味交易可能連結人類暴露。
不嘻嘻：眼鏡蛇野味鏈一牽，人類暴露也跟著上桌。
Prevalence, virulence profiles and antibiotic susceptibility patterns of Shiga toxin producing Escherichia coli O157:H7 among children 6-59 months in Longido, Arusha-Tanzania¶
Authors: Martin MM et al. | Journal: PLoS One | Date: 2026
DOI: 10.1371/journal.pone.0353396 | PMID: 42430368
TL;DR: 坦尚尼亞Longido 150名6–59月腹瀉兒童STEC盛行率13.3%；動物接觸、生乳與未處理飲水為獨立風險，ampicillin全數抗藥。
不嘻嘻：STEC加ampicillin全抗藥，兒科腸胃炎又更煩。
25 Years of Non-Human Primates Surveillance contributing to Yellow Fever control in Brazil¶
Authors: Passos PHO et al. | Journal: Acta Trop | Date: 2026 Jul 10
DOI: 10.1016/j.actatropica.2026.108227 | PMID: 42431568
TL;DR: 巴西1999–2025年通報35,496起非人靈長類YF epizootics，9.0%確診；與人類病例強相關（r=0.72），可作早期預警。
嘻嘻：先看猴子再防YF，公共衛生很懂前哨戰。
Molecular Detection of Balantioides coli in Pigs Employing the Traditional PCR and a Novel Cross-Priming Amplification-Based Lateral Flow Assay¶
Authors: Liu KH et al. | Journal: Transbound Emerg Dis | Date: 2026
DOI: 10.1155/tbed/4982345 | PMID: 42427278
TL;DR: 中國山西341份豬糞便中Balantioides coli盛行率75.1%，含具人畜共通潛力genotype I；新CPA-LFIA可於63分鐘內完成偵測。
嘻嘻：Balantioides coli快篩變快，豬場監測更有感。
Controlling foodborne antimicrobial-resistant bacteria: The gen(i)e is out of the bottle¶
Authors: Parker EM et al. | Journal: J Food Prot | Date: 2026 Jul 09
DOI: 10.1016/j.jfp.2026.100857 | PMID: 42425308
TL;DR: 食物是antibiotic-resistant bacteria傳播關鍵介面；僅減少農業抗生素不足，仍需agrifood stewardship與全食物鏈衛生控管並行。
不嘻嘻：食物鏈抗藥性這鍋，不能只怪農場抗生素。
🟡 Food Security / Food Safety¶
A MIL-88@Ru-based molecularly imprinted electrochemiluminescence sensor for highly selective and sensitive detection of enrofloxacin residues in animal-derived foods¶
Authors: Jiang J et al. | Journal: Food Chem | Date: 2026 Jul 07
DOI: 10.1016/j.foodchem.2026.150328 | PMID: 42431037
TL;DR: MIL-88@Ru MIP-ECL sensor偵測動物性食品enrofloxacin，線性範圍1 nmol/L–20 μmol/L、LOD 0.28 nmol/L，回收率97.7–106.4%。
嘻嘻：enrofloxacin殘留能抓到這麼低，檢驗魂醒了。
Mangiferin Attenuates Aflatoxin B1-Induced Ferroptosis by Activating of Nrf2-Signaling and Mitochondrial Biogenesis in Human Ovarian Granulosa Cells¶
Authors: Ruan CW et al. | Journal: Food Chem Toxicol | Date: 2026 Jul 10
DOI: 10.1016/j.fct.2026.116271 | PMID: 42431442
TL;DR: Mangiferin可透過活化Nrf2 signaling與mitochondrial biogenesis，減輕AFB1誘發人類卵巢granulosa cells oxidative stress與ferroptosis。
嘻嘻：Mangiferin救細胞有戲，Nrf2這次很給力。
Peer review of the pesticide risk assessment of the active substance Bacillus paralicheniformis strain FMCH001¶
Authors: Álvarez F et al. | Journal: EFSA J | Date: 2026 Jul
DOI: 10.2903/j.efsa.2026.10152 | PMID: 42434716
TL;DR: EFSA peer review評估Bacillus paralicheniformis strain FMCH001作為fungicide/nematicide之代表用途，列出regulatory risk assessment endpoints、缺漏資料與疑慮。
不嘻嘻：生物農藥審查細節多，資料缺口不會放假。
Mechanistic insights into acid-induced viable but non-culturable state formation regulated by asr in Escherichia coli O157:H7: roles of intracellular protein aggregation¶
Authors: Ma X et al. | Journal: Food Microbiol | Date: 2026 Dec
DOI: 10.1016/j.fm.2026.105200 | PMID: 42425671
TL;DR: 酸壓力30小時使E. coli O157:H7進入VBNC；asr上調促進胞內蛋白聚集與低ATP狀態，Δasr則無法形成VBNC。
不嘻嘻：E. coli O157:H7裝死進VBNC，食安人員苦笑。
Metabolomics-driven insights into the multi-target antibacterial mechanisms of 2-methoxycinnamaldehyde against Bacillus cereus and its application in pork preservation¶
Authors: Li X et al. | Journal: Food Microbiol | Date: 2026 Dec
DOI: 10.1016/j.fm.2026.105198 | PMID: 42425669
TL;DR: 2-methoxycinnamaldehyde對Bacillus cereus ATCC 11778 MIC 150 μg/mL、MBC 200 μg/mL；豬肉冷藏模型第7天完全清除菌量。
嘻嘻：2-methoxycinnamaldehyde讓豬肉保存多個選項。
Rapid and sensitive detection of Yersinia pseudotuberculosis in pork using recombinase polymerase amplification-based lateral flow strip and real-time fluorescence assays¶
Authors: Zhang X et al. | Journal: Food Microbiol | Date: 2026 Dec
DOI: 10.1016/j.fm.2026.105197 | PMID: 42425668
TL;DR: 針對豬肉Yersinia pseudotuberculosis偵測，RPA-LFS LOD 206 CFU/mL，RT-RPA可至103 CFU/mL；人工污染樣本準確率100%。
嘻嘻：豬肉裡找Yersinia pseudotuberculosis，快篩很可以。
Prevalence and antimicrobial resistance of Lactococcus petauri, L. formosensis, and L. garvieae in retail fish, Japan: A pilot study for antimicrobial resistance monitoring of gram-positive bacteria in seafoods¶
Authors: Fukuda A et al. | Journal: Food Microbiol | Date: 2026 Dec
DOI: 10.1016/j.fm.2026.105189 | PMID: 42425660
TL;DR: 日本490件市售魚中16.1%檢出Lactococcus，以L. petauri 8.8%最多；lincomycin抗藥率88.4%，並見多重抗藥plasmid。
不嘻嘻：魚貨裡的Lactococcus帶plasmid，監測不能偷懶。
Dynamics of Bacillus cereus during rearing of Hermetia illucens on authorized and unauthorized substrates under European legislation¶
Authors: Doublet B et al. | Journal: Food Microbiol | Date: 2026 Dec
DOI: 10.1016/j.fm.2026.105184 | PMID: 42425656
TL;DR: Hermetia illucens幼蟲無法顯著降低Bacillus cereus；授權與非授權基質所得幼蟲與frass皆持續帶高菌量，需後續處理降低風險。
不嘻嘻：黑水虻很努力，但Bacillus cereus沒在怕。
Comparative genomics and phenotypes of Listeria monocytogenes isolated from enoki mushrooms in South Korea and China¶
Authors: Hu WS et al. | Journal: Food Microbiol | Date: 2026 Dec
DOI: 10.1016/j.fm.2026.105182 | PMID: 42425654
TL;DR: 韓國與中國金針菇129件中Listeria monocytogenes陽性18.6%；分離株與歐美outbreak-related strains core-genome距離極近，提示全球供應鏈傳播。
不嘻嘻：金針菇供應鏈一串起來，Listeria也環遊世界。
Rational design of a sulfonium-stabilized cyclic temporin-SHf as a potential food preservative¶
Authors: Li W et al. | Journal: Food Microbiol | Date: 2026 Dec
DOI: 10.1016/j.fm.2026.105178 | PMID: 42425650
TL;DR: sulfonium-stabilized cyclic temporin-SHf提升穩定性與抗菌力約10倍；TP[4,7]-Ph在S. aureus豬肉模型降低菌生長並延緩品質劣化。
嘻嘻：cyclic temporin-SHf穩定升級，保鮮抗菌有新招。
Lactobacillus plantarum protects broilers against Salmonella Typhimurium infection via modulating TLR4/MyD88/NF-κB signaling pathway and gut microbiota¶
Authors: Wang L et al. | Journal: J Appl Microbiol | Date: 2026 Jul 10
DOI: 10.1093/jambio/lxag163 | PMID: 42429505
TL;DR: 80隻肉雞中，Lactobacillus plantarum LW減輕Salmonella Typhimurium造成的生長遲滯、oxidative stress與腸傷害，並調控TLR4/MyD88/NF-κB與gut microbiota。
嘻嘻：益生菌幫肉雞扛Salmonella Typhimurium，腸道隊友有用。
資料來源：PubMed (articles retrieved 2026-07-12)